Anaemia frequently develops in patients with chronic kidney disease (CKD) as the kidneys' ability to produce erythropoietin diminishes. Historically, treatment has relied on replacing this hormone with injectable agents like recombinant human erythropoietin (rhEPO).
This report delivers a targeted analysis of the anaemia treatment landscape in chronic kidney disease (CKD) within Japan, one of the world's most mature nephrology markets and an early adopter of a class of newer oral medications, HIF prolyl hydroxylase inhibitors (HIF-PHIs). Leveraging tracked market data between 2020-2022, this analysis provides evidence-based insights into treatment dynamics across dialysis and non-dialysis segments, and the competitive positioning and ongoing impact of HIF-PHIs following their launch vs traditional rhEPO.
As Japan was the first major market to adopt HIF-PHIs - with roxadustat approval in September 2019 - this report provides a strategic reference point for assessing how these therapies gained traction and what dynamics drove early prescriber behaviour. The definitive case study for de-risking the launch of novel therapies in a mature market.
Sample excerpt from report